Crystallization and preliminary diffraction studies of SFC-1, a carbapenemase conferring antibiotic resistance

SFC-1, a class A carbapenemase that confers antibiotic resistance, hydrolyzes the β-lactam rings of β-lactam antibiotics (carbapenems, cephalosporins, penicillins and aztreonam). SFC-1 presents an enormous challenge to infection control, particularly in the eradication of Gram-negative pathogens. As...

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Autores principales: Hong, Myoung-Ki, Lee, Jae Jin, Wu, Xing, Kim, Jin-Kwang, Jeong, Byeong Chul, Pham, Tan-Viet, Kim, Seung-Hwan, Lee, Sang Hee, Kang, Lin-Woo
Formato: Artigo
Lenguaje:Inglês
Publicado: International Union of Crystallography 2012
Materias:
Crystallization Communications
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3433214/
https://ncbi.nlm.nih.gov/pubmed/22949211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309112033702
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