Crystal structure of the human PRMT5:MEP50 complex

Protein arginine methyltransferases (PRMTs) play important roles in several cellular processes, including signaling, gene regulation, and transport of proteins and nucleic acids, to impact growth, differentiation, proliferation, and development. PRMT5 symmetrically di-methylates the two-terminal ω-g...

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Bibliographische Detailangaben
Hauptverfasser: Antonysamy, Stephen, Bonday, Zahid, Campbell, Robert M., Doyle, Brandon, Druzina, Zhanna, Gheyi, Tarun, Han, Bomie, Jungheim, Louis N., Qian, Yuewei, Rauch, Charles, Russell, Marijane, Sauder, J. Michael, Wasserman, Stephen R., Weichert, Kenneth, Willard, Francis S., Zhang, Aiping, Emtage, Spencer
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2012
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497828/
https://ncbi.nlm.nih.gov/pubmed/23071334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209814109
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