Crystal structure of the human PRMT5:MEP50 complex

Protein arginine methyltransferases (PRMTs) play important roles in several cellular processes, including signaling, gene regulation, and transport of proteins and nucleic acids, to impact growth, differentiation, proliferation, and development. PRMT5 symmetrically di-methylates the two-terminal ω-g...

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Detalhes bibliográficos
Main Authors: Antonysamy, Stephen, Bonday, Zahid, Campbell, Robert M., Doyle, Brandon, Druzina, Zhanna, Gheyi, Tarun, Han, Bomie, Jungheim, Louis N., Qian, Yuewei, Rauch, Charles, Russell, Marijane, Sauder, J. Michael, Wasserman, Stephen R., Weichert, Kenneth, Willard, Francis S., Zhang, Aiping, Emtage, Spencer
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497828/
https://ncbi.nlm.nih.gov/pubmed/23071334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1209814109
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