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PKA and GAB2 play central roles in the FSH signaling pathway to PI3K and AKT in ovarian granulosa cells

Controlled maturation of ovarian follicles is necessary for fertility. Follicles are restrained at an immature stage until stimulated by FSH secreted by pituitary gonadotropes. FSH acts on granulosa cells within the immature follicle to inhibit apoptosis, promote proliferation, stimulate production...

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Bibliografiske detaljer
Main Authors: Hunzicker-Dunn, Mary E., Lopez-Biladeau, Blanca, Law, Nathan C., Fiedler, Sarah E., Carr, Daniel W., Maizels, Evelyn T.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497822/
https://ncbi.nlm.nih.gov/pubmed/23045700
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1205661109
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