Induction of Cyclin D2 in Rat Granulosa Cells Requires FSH-dependent Relief from FOXO1 Repression Coupled with Positive Signals from Smad

Ovarian follicles undergo exponential growth in response to follicle-stimulating hormone (FSH), largely as a result of the proliferation of granulosa cells (GCs). In vitro under serum-free conditions, rat GCs differentiate in response to FSH but do not proliferate unless activin is also present. In...

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Detalhes bibliográficos
Main Authors: Park, Youngkyu, Maizels, Evelyn T., Feiger, Zachary J., Alam, Hena, Peters, Carl A., Woodruff, Teresa K., Unterman, Terry G., Lee, Eun Jig, Jameson, J. Larry, Hunzicker-Dunn, Mary
Formato: Artigo
Idioma:Inglês
Publicado em: 2004
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1564190/
https://ncbi.nlm.nih.gov/pubmed/15613482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M409486200
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