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Structural basis for multifunctional roles of mammalian aminopeptidase N

Mammalian aminopeptidase N (APN) plays multifunctional roles in many physiological processes, including peptide metabolism, cell motility and adhesion, and coronavirus entry. Here we determined crystal structures of porcine APN at 1.85 Å resolution and its complexes with a peptide substrate and a va...

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Hlavní autoři: Chen, Lang, Lin, Yi-Lun, Peng, Guiqing, Li, Fang
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497818/
https://ncbi.nlm.nih.gov/pubmed/23071329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210123109
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