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A Unified Mechanism for Aminopeptidase N-based Tumor Cell Motility and Tumor-homing Therapy
Tumor cell surface aminopeptidase N (APN or CD13) has two puzzling functions unrelated to its enzymatic activity: mediating tumor cell motility and serving as a receptor for tumor-homing peptides (peptides that bring anti-cancer drugs to tumor cells). To investigate APN-based tumor-homing therapy, w...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4263860/ https://ncbi.nlm.nih.gov/pubmed/25359769 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.566802 |
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