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Direct observation of a force-induced switch in the anisotropic mechanical unfolding pathway of a protein
Many biological processes generate force, and proteins have evolved to resist and respond to tension along different force axes. Single-molecule force spectroscopy allows for molecular insight into the behavior of proteins under force and the mechanism of protein folding in general. Here, we have us...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497811/ https://ncbi.nlm.nih.gov/pubmed/22949695 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201800109 |
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