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The molten globule state is unusually deformable under mechanical force

Recently, the role of force in cellular processes has become more evident, and now with advances in force spectroscopy, the response of proteins to force can be directly studied. Such studies have found that native proteins are brittle, and thus not very deformable. Here, we examine the mechanical p...

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Detalhes bibliográficos
Main Authors: Elms, Phillip J., Chodera, John D., Bustamante, Carlos, Marqusee, Susan
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3309780/
https://ncbi.nlm.nih.gov/pubmed/22355138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1115519109
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