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Quantifying internal friction in unfolded and intrinsically disordered proteins with single-molecule spectroscopy

Internal friction, which reflects the “roughness” of the energy landscape, plays an important role for proteins by modulating the dynamics of their folding and other conformational changes. However, the experimental quantification of internal friction and its contribution to folding dynamics has rem...

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מידע ביבליוגרפי
Main Authors: Soranno, Andrea, Buchli, Brigitte, Nettels, Daniel, Cheng, Ryan R., Müller-Späth, Sonja, Pfeil, Shawn H., Hoffmann, Armin, Lipman, Everett A., Makarov, Dmitrii E., Schuler, Benjamin
פורמט: Artigo
שפה:Inglês
יצא לאור: National Academy of Sciences 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497802/
https://ncbi.nlm.nih.gov/pubmed/22492978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1117368109
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