Estrogen receptor prevents p53-dependent apoptosis in breast cancer

More than two-thirds of breast cancers express the estrogen receptor (ER) and depend on estrogen for growth and survival. Therapies targeting ER function, including aromatase inhibitors that block the production of estrogens and ER antagonists that alter ER transcriptional activity, play a central r...

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Bibliografiske detaljer
Main Authors: Bailey, Shannon T., Shin, Hyunjin, Westerling, Thomas, Liu, Xiaole Shirley, Brown, Myles
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497783/
https://ncbi.nlm.nih.gov/pubmed/23077249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1018858109
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