Targeting Androgen Receptor in Estrogen Receptor-Negative Breast Cancer

Endocrine therapies for breast cancer that target the estrogen receptor (ER) are ineffective in the 25-30% of cases that are ER negative (ER−). Androgen receptor (AR) is expressed in 60-70% of breast tumors, independent of ER status. How androgens and AR regulate breast cancer growth remains largely...

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Bibliografiske detaljer
Main Authors: Ni, Min, Chen, Yiwen, Lim, Elgene, Wimberly, Hallie, Bailey, Shannon T., Imai, Yuuki, Rimm, David L., Liu, X. Shirley, Brown, Myles
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180861/
https://ncbi.nlm.nih.gov/pubmed/21741601
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2011.05.026
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