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Transiently populated intermediate functions as a branching point of the FF domain folding pathway

Studies of protein folding and the intermediates that are formed along the folding pathway provide valuable insights into the process by which an unfolded ensemble forms a functional native conformation. However, because intermediates on folding pathways can serve as initiation points of aggregation...

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Autors principals: Korzhnev, Dmitry M., Religa, Tomasz L., Kay, Lewis E.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497754/
https://ncbi.nlm.nih.gov/pubmed/22647611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201799109
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