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Overcoming multidrug-resistance in vitro and in vivo using the novel P-glycoprotein inhibitor 1416
MDR (multidrug-resistance) represents a major obstacle to successful cancer chemotherapy and is usually accomplished by overexpression of P-gp (P-glycoprotein). Much effort has been devoted to developing P-gp inhibitors to modulate MDR. However, none of the inhibitors on the market have been success...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3497725/ https://ncbi.nlm.nih.gov/pubmed/22757751 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20120020 |
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