Constraints on Viral Evolution during Chronic Hepatitis C Virus Infection Arising from a Common-Source Exposure

Extraordinary viral sequence diversity and rapid viral genetic evolution are hallmarks of hepatitis C virus (HCV) infection. Viral sequence evolution has previously been shown to mediate escape from cytotoxic T-lymphocyte (CTL) and neutralizing antibody responses in acute HCV infection. HCV evolutio...

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Detalhes bibliográficos
Main Authors: Bailey, Justin R., Laskey, Sarah, Wasilewski, Lisa N., Munshaw, Supriya, Fanning, Liam J., Kenny-Walsh, Elizabeth, Ray, Stuart C.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Genetic Diversity and Evolution
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497661/
https://ncbi.nlm.nih.gov/pubmed/22973048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01440-12
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