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Divergent and convergent evolution after a common-source outbreak of hepatitis C virus
The genomic sequences of viruses that are highly mutable and cause chronic infection tend to diverge over time. We report that these changes represent both immune-driven selection and, in the absence of immune pressure, reversion toward an ancestral consensus. Sequence changes in hepatitis C virus (...
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| Autors principals: | , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
The Rockefeller University Press
2005
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2213258/ https://ncbi.nlm.nih.gov/pubmed/15939791 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20050122 |
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