Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue

Through analysis of mice with spatially and temporally restricted inactivation of Lpin1, we characterized its cell autonomous function in both white (WAT) and brown (BAT) adipocyte development and maintenance. We observed that the lipin 1 inactivation in adipocytes of aP2(Cre/+)/Lp(fEx2)(-)(3/fEx2)(...

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Main Authors: Nadra, Karim, Médard, Jean-Jacques, Mul, Joram D., Han, Gil-Soo, Grès, Sandra, Pende, Mario, Metzger, Daniel, Chambon, Pierre, Cuppen, Edwin, Saulnier-Blache, Jean-Sébastien, Carman, George M., Desvergne, Béatrice, Chrast, Roman
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497595/
https://ncbi.nlm.nih.gov/pubmed/23028044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00512-12
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