Cell Autonomous Lipin 1 Function Is Essential for Development and Maintenance of White and Brown Adipose Tissue

Through analysis of mice with spatially and temporally restricted inactivation of Lpin1, we characterized its cell autonomous function in both white (WAT) and brown (BAT) adipocyte development and maintenance. We observed that the lipin 1 inactivation in adipocytes of aP2(Cre/+)/Lp(fEx2)(-)(3/fEx2)(...

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Detalhes bibliográficos
Main Authors: Nadra, Karim, Médard, Jean-Jacques, Mul, Joram D., Han, Gil-Soo, Grès, Sandra, Pende, Mario, Metzger, Daniel, Chambon, Pierre, Cuppen, Edwin, Saulnier-Blache, Jean-Sébastien, Carman, George M., Desvergne, Béatrice, Chrast, Roman
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497595/
https://ncbi.nlm.nih.gov/pubmed/23028044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00512-12
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