Equal sensitivity of Cav1.2 and Cav1.3 channels to the opposing modulations of PKA and PKG in mouse chromaffin cells

Mouse chromaffin cells (MCCs) express high densities of L-type Ca(2+) channels (LTCCs), which control pacemaking activity and catecholamine secretion proportionally to their density of expression. In vivo phosphorylation of LTCCs by cAMP–PKA and cGMP–PKG, regulate LTCC gating in two opposing ways: t...

Full description

Saved in:
Bibliographic Details
Main Authors: Mahapatra, Satyajit, Marcantoni, Andrea, Zuccotti, Annalisa, Carabelli, Valentina, Carbone, Emilio
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2012
Subjects:
Molecular and Cellular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497563/
https://ncbi.nlm.nih.gov/pubmed/22826131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2012.236729
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items