Bacteria mature preproinsulin to proinsulin.
By inserting the rat preproinsulin gene into the bacterial prepenicillinase gene, we formed a variety of hybrid bacterial-eukaryotic signal sequences attached to proinsulin. Among these were the four following constructions: rat proinsulin attached to the entire penicillinase signal sequence and rat...
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| Publicado en: | Proc Natl Acad Sci U S A |
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| Autores principales: | , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
National Academy of Sciences
1980
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349753/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7001451/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.3988 |
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