Studies on the secretion of newly synthesized proinsulin and insulin from isolated rat islets of langerhans

Islets of Langerhans isolated from rat pancreas were incubated at 37°C(95% O(2)/5% CO(2)) in buffered medium containing 1.0 mg/ml glucose and leucine (3)H for 1 hr (1st hr), washed, and incubated for an additional hr (2nd hr) in low glucose medium (0.5-1.0 mg/ml) containing unlabeled leucine. A port...

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Publié dans:	J Clin Invest
Auteurs principaux:	Sando, Hiroyuki, Borg, Jo, Steiner, Donald F.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Clinical Investigation 1972
Sujets:	Articles
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC292285/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/4336941/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI106944
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