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Bacteria mature preproinsulin to proinsulin.

By inserting the rat preproinsulin gene into the bacterial prepenicillinase gene, we formed a variety of hybrid bacterial-eukaryotic signal sequences attached to proinsulin. Among these were the four following constructions: rat proinsulin attached to the entire penicillinase signal sequence and rat...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Talmadge, K, Kaufman, J, Gilbert, W
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 1980
Предметы:
Online-ссылка:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349753/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7001451/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.7.3988
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