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Involvement of Oxidative Stress in Suppression of Insulin Biosynthesis under Diabetic Conditions

Type 2 diabetes is characterized by pancreatic β-cell dysfunction and insulin resistance, and the number of patients has markedly increased worldwide. In the diabetic state, hyperglycemia per se and subsequent induction of oxidative stress decrease insulin biosynthesis and secretion, leading to the...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Kaneto, Hideaki, Matsuoka, Taka-aki
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Molecular Diversity Preservation International (MDPI) 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497347/
https://ncbi.nlm.nih.gov/pubmed/23202973
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms131013680
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