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Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence Expression In Vivo

Fluoride is the mainstay of dental caries prevention, and yet current applications offer incomplete protection and may not effectively address the infectious character of the disease. Therefore, we evaluated the effectiveness of a novel combination therapy (CT; 2 mM myricetin, 4 mM tt-farnesol, 250...

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Autors principals: Falsetta, Megan L., Klein, Marlise I., Lemos, José A., Silva, Bruno B., Agidi, Senyo, Scott-Anne, Kathy K., Koo, Hyun
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497192/
https://ncbi.nlm.nih.gov/pubmed/22985885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01381-12
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