Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence Expression In Vivo

Fluoride is the mainstay of dental caries prevention, and yet current applications offer incomplete protection and may not effectively address the infectious character of the disease. Therefore, we evaluated the effectiveness of a novel combination therapy (CT; 2 mM myricetin, 4 mM tt-farnesol, 250...

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Bibliographic Details
Main Authors: Falsetta, Megan L., Klein, Marlise I., Lemos, José A., Silva, Bruno B., Agidi, Senyo, Scott-Anne, Kathy K., Koo, Hyun
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497192/
https://ncbi.nlm.nih.gov/pubmed/22985885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01381-12
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