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Novel Antibiofilm Chemotherapy Targets Exopolysaccharide Synthesis and Stress Tolerance in Streptococcus mutans To Modulate Virulence Expression In Vivo

Fluoride is the mainstay of dental caries prevention, and yet current applications offer incomplete protection and may not effectively address the infectious character of the disease. Therefore, we evaluated the effectiveness of a novel combination therapy (CT; 2 mM myricetin, 4 mM tt-farnesol, 250...

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Main Authors: Falsetta, Megan L., Klein, Marlise I., Lemos, José A., Silva, Bruno B., Agidi, Senyo, Scott-Anne, Kathy K., Koo, Hyun
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497192/
https://ncbi.nlm.nih.gov/pubmed/22985885
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01381-12
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