Fks1 and Fks2 Are Functionally Redundant but Differentially Regulated in Candida glabrata: Implications for Echinocandin Resistance

The echinocandins caspofungin, micafungin, and anidulafungin, inhibitors of cell wall β-1,3-glucan synthesis, were recently elevated to first-line agents for treating infections due to the azole-refractory yeast Candida glabrata. In Candida albicans, echinocandin resistance is strictly associated wi...

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Autors principals: Katiyar, Santosh K., Alastruey-Izquierdo, Ana, Healey, Kelley R., Johnson, Michael E., Perlin, David S., Edlind, Thomas D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2012
Matèries:
Mechanisms of Resistance
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3497156/
https://ncbi.nlm.nih.gov/pubmed/23027185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00813-12
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