ERG and FLI1 binding sites demarcate targets for aberrant epigenetic regulation by AML1-ETO in acute myeloid leukemia

ERG and FLI1 are closely related members of the ETS family of transcription factors and have been identified as essential factors for the function and maintenance of normal hematopoietic stem cells. Here genome-wide analysis revealed that both ERG and FLI1 occupy similar genomic regions as AML1-ETO...

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Autors principals: Martens, Joost H. A., Mandoli, Amit, Simmer, Femke, Wierenga, Bart-Jan, Saeed, Sadia, Singh, Abhishek A., Altucci, Lucia, Vellenga, Edo, Stunnenberg, Hendrik G.
Format: Artigo
Idioma:Inglês
Publicat: American Society of Hematology 2012
Matèries:
Myeloid Neoplasia
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496958/
https://ncbi.nlm.nih.gov/pubmed/22983443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2012-05-429050
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