Glucocorticoid receptor mRNA and protein isoform alterations in the orbitofrontal cortex in schizophrenia and bipolar disorder

BACKGROUND: The orbitofrontal cortex (OFC) may play a role in the pathogenesis of psychiatric illnesses such as bipolar disorder and schizophrenia, in which hypothalamic-pituitary-adrenal (HPA) axis abnormalities are observed and stress has been implicated. A critical component of the HPA axis which...

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Bibliographic Details
Main Authors: Sinclair, Duncan, Webster, Maree J, Fullerton, Janice M, Weickert, Cynthia Shannon
Format: Artigo
Language:Inglês
Published: BioMed Central 2012
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496870/
https://ncbi.nlm.nih.gov/pubmed/22812453
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-244X-12-84
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