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Glucocorticoid Receptor 1B and 1C mRNA Transcript Alterations in Schizophrenia and Bipolar Disorder, and Their Possible Regulation by GR Gene Variants

Abnormal patterns of HPA axis activation, under basal conditions and in response to stress, are found in individuals with schizophrenia and bipolar disorder. Altered glucocorticoid receptor (GR) mRNA and protein expression in the dorsolateral prefrontal cortex (DLPFC) in psychiatric illness have als...

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Detalhes bibliográficos
Main Authors: Sinclair, Duncan, Fullerton, Janice M., Webster, Maree J., Shannon Weickert, Cynthia
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3302776/
https://ncbi.nlm.nih.gov/pubmed/22427805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0031720
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