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Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness

Molecular abnormalities within the glucocorticoid receptor (GR) stress signaling pathway may confer, or reflect, susceptibility to stress in schizophrenia and bipolar disorder, but the extent of such abnormalities in the brain is not known. Using RNA-Seq and qPCR in two postmortem cohorts totaling 5...

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Detalhes bibliográficos
Main Authors: Sinclair, Duncan, Fillman, Stu G., Webster, Maree J., Weickert, Cynthia Shannon
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866598/
https://ncbi.nlm.nih.gov/pubmed/24345775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03539
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