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Dysregulation of glucocorticoid receptor co-factors FKBP5, BAG1 and PTGES3 in prefrontal cortex in psychotic illness

Molecular abnormalities within the glucocorticoid receptor (GR) stress signaling pathway may confer, or reflect, susceptibility to stress in schizophrenia and bipolar disorder, but the extent of such abnormalities in the brain is not known. Using RNA-Seq and qPCR in two postmortem cohorts totaling 5...

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Sonraí Bibleagrafaíochta
Main Authors: Sinclair, Duncan, Fillman, Stu G., Webster, Maree J., Weickert, Cynthia Shannon
Formáid: Artigo
Teanga:Inglês
Foilsithe: Nature Publishing Group 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3866598/
https://ncbi.nlm.nih.gov/pubmed/24345775
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep03539
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