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Increases in [(3)H]Muscimol and [(3)H]Flumazenil Binding in the Dorsolateral Prefrontal Cortex in Schizophrenia Are Linked to α4 and γ2S mRNA Levels Respectively

BACKGROUND: GABA(A) receptors (GABA(A)R) are composed of several subunits that determine sensitivity to drugs, synaptic localisation and function. Recent studies suggest that agonists targeting selective GABA(A)R subunits may have therapeutic value against the cognitive impairments observed in schiz...

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Main Authors: Verdurand, Mathieu, Fillman, Stu G., Shannon Weickert, Cynthia, Zavitsanou, Katerina
Formáid: Artigo
Teanga:Inglês
Foilsithe: Public Library of Science 2013
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540049/
https://ncbi.nlm.nih.gov/pubmed/23320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052724
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