Increases in [(3)H]Muscimol and [(3)H]Flumazenil Binding in the Dorsolateral Prefrontal Cortex in Schizophrenia Are Linked to α4 and γ2S mRNA Levels Respectively

BACKGROUND: GABA(A) receptors (GABA(A)R) are composed of several subunits that determine sensitivity to drugs, synaptic localisation and function. Recent studies suggest that agonists targeting selective GABA(A)R subunits may have therapeutic value against the cognitive impairments observed in schiz...

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Bibliografske podrobnosti
Main Authors: Verdurand, Mathieu, Fillman, Stu G., Shannon Weickert, Cynthia, Zavitsanou, Katerina
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2013
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540049/
https://ncbi.nlm.nih.gov/pubmed/23320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052724
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