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Increases in [(3)H]Muscimol and [(3)H]Flumazenil Binding in the Dorsolateral Prefrontal Cortex in Schizophrenia Are Linked to α4 and γ2S mRNA Levels Respectively

BACKGROUND: GABA(A) receptors (GABA(A)R) are composed of several subunits that determine sensitivity to drugs, synaptic localisation and function. Recent studies suggest that agonists targeting selective GABA(A)R subunits may have therapeutic value against the cognitive impairments observed in schiz...

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Detalhes bibliográficos
Main Authors: Verdurand, Mathieu, Fillman, Stu G., Shannon Weickert, Cynthia, Zavitsanou, Katerina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3540049/
https://ncbi.nlm.nih.gov/pubmed/23320076
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0052724
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