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Rapamycin has age-, treatment paradigm-, and model-specific anticonvulsant effects and modulates NPY expression in rats

PURPOSE: Rapamycin (RAP) has certain antiepileptogenic features. However, it is unclear whether these effects can be explained by the anticonvulsant action of RAP, which has not been studied yet. To address this question, we tested potential anticonvulsant effects of RAP in immature and adult rats u...

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Hlavní autoři: Chachua, Tamar, Poon, Ka-Lai, Yum, Mi-Sun, Nesheiwat, Leigh, DeSantis, Kara, Velíšková, Jana, Velíšek, Libor
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496841/
https://ncbi.nlm.nih.gov/pubmed/23016669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2012.03674.x
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