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Rapamycin has age-, treatment paradigm-, and model-specific anticonvulsant effects and modulates NPY expression in rats

PURPOSE: Rapamycin (RAP) has certain antiepileptogenic features. However, it is unclear whether these effects can be explained by the anticonvulsant action of RAP, which has not been studied yet. To address this question, we tested potential anticonvulsant effects of RAP in immature and adult rats u...

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Detalhes bibliográficos
Main Authors: Chachua, Tamar, Poon, Ka-Lai, Yum, Mi-Sun, Nesheiwat, Leigh, DeSantis, Kara, Velíšková, Jana, Velíšek, Libor
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496841/
https://ncbi.nlm.nih.gov/pubmed/23016669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2012.03674.x
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