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β-Estradiol Unmasks Metabotropic Receptor-Mediated Metaplasticity of NMDA Receptor Transmission in the Female rat Dentate Gyrus

Loss of estrogen in women following menopause is associated with increased risk for cognitive decline, dementia and depression, all of which can be prevented by estradiol replacement. The dentate gyrus plays an important role in cognition, learning and memory. The gatekeeping function of the dentate...

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Bibliographic Details
Main Authors: Nebieridze, Nino, Zhang, Xiao-lei, Chachua, Tamar, Velíšek, Libor, Stanton, Patric K., Velíšková, Jana
Format: Artigo
Language:Inglês
Published: 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3432293/
https://ncbi.nlm.nih.gov/pubmed/22541715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.psyneuen.2012.03.023
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