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Synthesis of Water Soluble Camptothecin-Polyoxetane Conjugates via Click Chemistry
Water soluble camptothecin (CPT)-polyoxetane conjugates were synthesized using a clickable polymeric platform P(EAMO) that was made by polymerization of acetylene-functionalized 3-ethyl-3-hydroxymethyl oxetane (i.e., EAMO). CPT was first modified with a linker 6-azidohexanoic acid via an ester linka...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496795/ https://ncbi.nlm.nih.gov/pubmed/23051100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp3005066 |
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