17-AAG Kills Intracellular Leishmania amazonensis while Reducing Inflammatory Responses in Infected Macrophages

BACKGROUND: Leishmaniasis is a neglected endemic disease with a broad spectrum of clinical manifestations. Pentavalent antimonials have been the treatment of choice for the past 70 years and, due to the emergence of resistant cases, the efficacy of these drugs has come under scrutiny. Second-line dr...

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Main Authors: Petersen, Antonio Luis de Oliveira Almeida, Guedes, Carlos Eduardo Sampaio, Versoza, Carolina Leite, Lima, José Geraldo Bomfim, de Freitas, Luiz Antônio Rodrigues, Borges, Valéria Matos, Veras, Patrícia Sampaio Tavares
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496716/
https://ncbi.nlm.nih.gov/pubmed/23152914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049496
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