17-AAG Kills Intracellular Leishmania amazonensis while Reducing Inflammatory Responses in Infected Macrophages

BACKGROUND: Leishmaniasis is a neglected endemic disease with a broad spectrum of clinical manifestations. Pentavalent antimonials have been the treatment of choice for the past 70 years and, due to the emergence of resistant cases, the efficacy of these drugs has come under scrutiny. Second-line dr...

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Main Authors: Petersen, Antonio Luis de Oliveira Almeida, Guedes, Carlos Eduardo Sampaio, Versoza, Carolina Leite, Lima, José Geraldo Bomfim, de Freitas, Luiz Antônio Rodrigues, Borges, Valéria Matos, Veras, Patrícia Sampaio Tavares
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2012
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496716/
https://ncbi.nlm.nih.gov/pubmed/23152914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049496
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