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Substrate Mediated Enzyme Prodrug Therapy
In this report, we detail Substrate Mediated Enzyme Prodrug Therapy (SMEPT) as a novel approach in drug delivery which relies on enzyme-functionalized cell culture substrates to achieve a localized conversion of benign prodrug(s) into active therapeutics with subsequent delivery to adhering cells or...
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| Auteurs principaux: | , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2012
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496709/ https://ncbi.nlm.nih.gov/pubmed/23152927 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0049619 |
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