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Chromosome-mediated gene transfer results in two classes of unstable transformants.
The human thymidine kinase gene has been transferred from HeLa S3 cells to mouse LM(TK-) cells via isolated metaphase chromosomes. Efficient transfer of the thymidine kinase gene (1.8 X 10(-5) colonies per recipient cell) was obtained when the donor chromosomes were precipitated with calcium phospha...
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| Publicado no: | Proc Natl Acad Sci U S A |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1980
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349667/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6932038/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.6.3610 |
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