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Chromosome-mediated gene transfer results in two classes of unstable transformants.

The human thymidine kinase gene has been transferred from HeLa S3 cells to mouse LM(TK-) cells via isolated metaphase chromosomes. Efficient transfer of the thymidine kinase gene (1.8 X 10(-5) colonies per recipient cell) was obtained when the donor chromosomes were precipitated with calcium phospha...

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Detalhes bibliográficos
Main Authors: Klobutcher, L A, Miller, C L, Ruddle, F H
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC349667/
https://ncbi.nlm.nih.gov/pubmed/6932038
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