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Mechanisms of DNA uptake by mammalian cells: fate of exogenously added DNA monitored by the use of fluorescent dyes.

Coprecipitation of DNA with calcium phosphate is a commonly used method of gene transfer in mammalian cells. We have found that DNA forms a tight complex with Ca Pi and that DNA in this complex is resistant to nucleases present in serum or added externally. Under optimal conditions, virtually all of...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Loyter, A, Scangos, G A, Ruddle, F H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1982
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC345755/
https://ncbi.nlm.nih.gov/pubmed/6952193
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