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Genetics of cell surface receptors for bioactive polypeptides: Binding of epidermal growth factor is associated with the presence of human chromosome 7 in human-mouse cell hybrids

Mouse A9 cells, L-cell-derived mutants deficient in hypoxanthine phosphoribosyltransferase (HPRT; IMP:pyrophosphate phosphoribosyltransferase, EC 2.4.2.8) were found to be incapable of binding (125)I-labeled epidermal growth factor (EGF) to the cell surface. The A9 cells were fused with human diploi...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Proc Natl Acad Sci U S A
Egile Nagusiak: Shimizu, Nobuyoshi, Behzadian, M. Ali, Shimizu, Yoshiko
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 1980
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC349665/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/6968072/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.77.6.3600
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