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Presence of human chromosome 21 alone is sufficient for hybrid cell sensitivity to human interferon.

Human/mouse somatic cell hybrids with chromosome 21 as the only detectable human genetic material were sensitive to both human leukocyte and fibroblast interferons. The presence of additional human chromosomes decreased the amount of interferon needed to attain a given level of virus resistance. Dec...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Slate, D L, Shulman, L, Lawrence, J B, Revel, M, Ruddle, F H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1978
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC353929/
https://ncbi.nlm.nih.gov/pubmed/202744
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