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Regulation of APC/C-Cdh1 and Its Function in Neuronal Survival

Neurons are post-mitotic cells that undergo an active downregulation of cell cycle-related proteins to survive. The activity of the anaphase-promoting complex/cyclosome (APC/C), an E3 ubiquitin ligase that regulates cell cycle progression in proliferating cells, plays a relevant role in post-mitotic...

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Detalhes bibliográficos
Autor principal: Almeida, Angeles
Formato: Artigo
Idioma:Inglês
Publicado em: Humana Press Inc 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496556/
https://ncbi.nlm.nih.gov/pubmed/22836916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-012-8309-2
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