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Investigation of the Polymeric Properties of α-Synuclein and Comparison with NMR Experiments: A Replica Exchange Molecular Dynamics Study

Intrinsically disordered proteins (IDPs) have been shown to be involved in a number of cellular functions, in addition to their predominance in diseased states. α-synuclein may be described as one such IDP implicated in the pathology of Parkinson’s disease. Understanding the conformational character...

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Bibliografiske detaljer
Main Authors: Narayanan, Chitra, Weinstock, Daniel S., Wu, Kuen-Phon, Baum, Jean, Levy, Ronald M.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496295/
https://ncbi.nlm.nih.gov/pubmed/23162382
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ct300241t
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