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Detection of transient inter-chain interactions in the intrinsically disordered protein α-synuclein by NMR paramagnetic relaxation enhancement
NMR paramagnetic relaxation enhancement experiments (PREs) have been applied to the intrinsically disordered protein α-synuclein, the primary protein in Parkinson’s disease, to directly characterize transient intermolecular complexes at neutral and low pH. At neutral pH, we observe weak N- to C-term...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3064441/ https://ncbi.nlm.nih.gov/pubmed/20359221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja9105495 |
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