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Focal adhesion kinase contributes to proliferative potential of ErbB2 mammary tumour cells but is dispensable for ErbB2 mammary tumour induction in vivo
INTRODUCTION: Activation of focal adhesion kinase (FAK) is hypothesized to play an important role in the pathogenesis of human breast cancer. METHODS: To directly evaluate the role of FAK in mammary tumour progression, we have used a conditional FAK mouse model and mouse mammary tumour virus (MMTV)-...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
BioMed Central
2012
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3496154/ https://ncbi.nlm.nih.gov/pubmed/22373082 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3131 |
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