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MicroRNA let-7a suppresses breast cancer cell migration and invasion through downregulation of C-C chemokine receptor type 7

INTRODUCTION: C-C chemokine receptor type 7 (CCR7) plays an important role in chemotactic and metastatic responses in various cancers, including breast cancer. In the present study, the authors demonstrated that microRNA (miRNA) let-7a downregulates CCR7 expression and directly influences the migrat...

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Detalhes bibliográficos
Main Authors: Kim, Seok-Jun, Shin, Ji-Young, Lee, Kang-Duck, Bae, Young-Ki, Sung, Ki Woong, Nam, Seok Jin, Chun, Kyung-Hee
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3496131/
https://ncbi.nlm.nih.gov/pubmed/22251626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/bcr3098
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