MicroRNA let-7 suppresses nasopharyngeal carcinoma cells proliferation through downregulating c-Myc expression

AIMS: This study aimed at evaluating the potential anti-proliferative effects of the microRNA let-7 family in nasopharyngeal carcinoma (NPC) cells. In addition, the association between let-7 suppression and DNA hypermethylation is examined. MATERIALS AND METHODS: Levels of mature let-7 family member...

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Hauptverfasser: Wong, Thian-Sze, Man, On-Ying, Tsang, Chi-Man, Tsao, Sai-Wah, Tsang, Ramond King-Yin, Chan, Jimmy Yu-Wai, Ho, Wai-Kuen, Wei, William Ignace, To, Victor Shing-Howe
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer-Verlag 2010
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Original Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3036828/
https://ncbi.nlm.nih.gov/pubmed/20440510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00432-010-0898-4
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